Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2009 Nov 17;106(46):19207-8.
doi: 10.1073/pnas.0911232106. Epub 2009 Nov 11.

How to learn new and interesting things from model systems based on "exotic" biological species

Affiliations
Comment

How to learn new and interesting things from model systems based on "exotic" biological species

John M Sedivy. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Naked mole rats and their cells. (Left) Adult naked mole rats. (Right) Fibroblasts cultured from adult naked mole rat dermis in a state of early contact inhibition. A similar culture of mouse or human cells would continue to grow until the surface of the dish was completely covered with crowded cells. In contrast, the culture of naked mole rat cells shown here has completely ceased proliferation.

Comment on

References

    1. Monod J, Jacob F. Teleonomic mechanisms in cellular metabolism, growth, and differentiation. Cold Spring Harbor Symp Quant Biol. 1961;26:389–401. - PubMed
    1. Seluanov A, et al. Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole rat. Proc Natl Acad Sci USA. 2009;106:19352–19357. - PMC - PubMed
    1. Buffenstein R, Jarvis JU. The naked mole rat: A new record for the oldest living rodent. Sci Aging Knowledge Environ. 2002;2002:pe7. - PubMed
    1. de Magalhaes JP, Costa J. A database of vertebrate longevity records and their relation to other life-history traits. J Evol Biol. 2009;22:1770–1774. - PubMed
    1. Buffenstein R. Negligible senescence in the longest-living rodent, the naked mole rat: Insights from a successfully aging species. J Comp Physiol B. 2008;178:439–445. - PubMed

LinkOut - more resources