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. 2010 Jul;81(5):367-70.
doi: 10.1016/j.fitote.2009.11.003. Epub 2009 Nov 10.

A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum

Yue Kong  1 , Jun-Jun Xiao, Shu-Cong Meng, Xiao-Min Dong, Yue-Wei Ge, Ru-Feng Wang, Ming-Ying Shang, Shao-Qing Cai
Affiliations

A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum

Yue Kong et al. Fitoterapia. 2010 Jul.

Abstract

Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2'-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2'-diprenylquercetin 3-methyl ether exhibited cytotoxic activities against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time.

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