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. 2010 Jan;38(Database issue):D46-51.
doi: 10.1093/nar/gkp1024. Epub 2009 Nov 12.

GenBank

Dennis A Benson  1 , Ilene Karsch-Mizrachi, David J Lipman, James Ostell, Eric W Sayers
Affiliations

GenBank

Dennis A Benson et al. Nucleic Acids Res. 2010 Jan.

Abstract

GenBank is a comprehensive database that contains publicly available nucleotide sequences for more than 300,000 organisms named at the genus level or lower, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bi-monthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI homepage: www.ncbi.nlm.nih.gov.

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References

    1. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Sayers EW. GenBank. Nucleic Acids Res. 2010;38:D46–D51. - PMC - PubMed
    1. Kulikova T, Akhtar R, Aldebert P, Althorpe N, Andersson M, Baldwin A, Bates K, Bhattacharyya S, Bower L, Browne P, et al. EMBL nucleotide sequence database in 2006. Nucleic Acids Res. 2007;35:D16–D20. - PMC - PubMed
    1. Sugawara H, Ogasawara O, Okubo K, Gojobori T, Tateno Y. DDBJ with new system and face. Nucleic Acids Res. 2008;36:D22–D24. - PMC - PubMed
    1. Sayers EW, Barrett T, Benson DA, Bryant SH, Canese K, Chetvernin V, Church DM, Dicuccio M, Edgar R, Federhen S, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2010;38:D5–D16. - PMC - PubMed
    1. Boguski MS, Lowe TM, Tolstoshev CM. dbEST–database for “expressed sequence tags”. Nat. Genet. 1993;4:332–333. - PubMed

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