Safety profile of IBD: lymphoma risks
- PMID: 19913208
- DOI: 10.1016/j.gtc.2009.07.004
Safety profile of IBD: lymphoma risks
Abstract
This article describes the cancer risks of commonly used inflammatory bowel disease (IBD) medications, with an emphasis on hematologic malignancy risks. The increasing use of immunosuppressant therapies in the treatment of IBD has raised this question to an even greater importance. Studies evaluating these medications are complicated due to varying disease severity and concomitant use of other immunosuppressant medication. The potential risks of all therapies must be weighed against the benefits these therapies can offer these patients.
Republished in
-
Safety profile of IBD: lymphoma risks.Med Clin North Am. 2010 Jan;94(1):93-113. doi: 10.1016/j.mcna.2009.08.015. Med Clin North Am. 2010. PMID: 19944800
Similar articles
-
Safety profile of IBD: lymphoma risks.Med Clin North Am. 2010 Jan;94(1):93-113. doi: 10.1016/j.mcna.2009.08.015. Med Clin North Am. 2010. PMID: 19944800
-
Lymphoma in inflammatory bowel disease and treatment decisions.Am J Gastroenterol. 2012 Jul;107(7):964-70. doi: 10.1038/ajg.2011.479. Am J Gastroenterol. 2012. PMID: 22764018 Review.
-
The risk of lymphoma in the treatment of inflammatory bowel disease with immunosuppressive agents.Crit Rev Oncol Hematol. 2005 Oct;56(1):169-78. doi: 10.1016/j.critrevonc.2005.02.004. Crit Rev Oncol Hematol. 2005. PMID: 15979323 Review.
-
Malignant neoplasms subsequent to treatment of inflammatory bowel disease with 6-mercaptopurine.Am J Gastroenterol. 1999 Nov;94(11):3248-53. doi: 10.1111/j.1572-0241.1999.01530.x. Am J Gastroenterol. 1999. PMID: 10566724
-
Treatment with biologic therapies and the risk of cancer in patients with IBD.Nat Clin Pract Gastroenterol Hepatol. 2007 Feb;4(2):78-91. doi: 10.1038/ncpgasthep0695. Nat Clin Pract Gastroenterol Hepatol. 2007. PMID: 17268543 Review.
Cited by
-
Primary effusion lymphoma-like lymphoma in a patient with inflammatory bowel disease.World J Gastroenterol. 2014 Jan 21;20(3):857-62. doi: 10.3748/wjg.v20.i3.857. World J Gastroenterol. 2014. PMID: 24574759 Free PMC article.
-
Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases.Aliment Pharmacol Ther. 2015 Jun;41(11):1141-8. doi: 10.1111/apt.13195. Epub 2015 Apr 13. Aliment Pharmacol Ther. 2015. PMID: 25864945 Free PMC article.
-
Top-down therapy for IBD: rationale and requisite evidence.Nat Rev Gastroenterol Hepatol. 2010 Feb;7(2):86-92. doi: 10.1038/nrgastro.2009.222. Nat Rev Gastroenterol Hepatol. 2010. PMID: 20134490 Review.
-
Risk of lymphoma in patients with inflammatory bowel disease.Gastroenterol Hepatol (N Y). 2012 Jan;8(1):45-7. Gastroenterol Hepatol (N Y). 2012. PMID: 22347833 Free PMC article. No abstract available.
-
The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease.Aliment Pharmacol Ther. 2017 Jul;46(2):162-168. doi: 10.1111/apt.14125. Epub 2017 May 3. Aliment Pharmacol Ther. 2017. PMID: 28470787 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical