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. 2011 Jan;187(1):139-41.
doi: 10.1016/j.tvjl.2009.10.013. Epub 2009 Nov 14.

Characterisation of ceftiofur resistance in swine bacterial pathogens

Yogesh Chander  1 , Simone Oliveira, Sagar M Goyal
Affiliations

Characterisation of ceftiofur resistance in swine bacterial pathogens

Yogesh Chander et al. Vet J. 2011 Jan.

Abstract

A PCR based method was developed for the identification of ceftiofur resistance genes (bla(CMY-2), bla(TEM-1), and ampC) in swine bacterial pathogens. Using this method, the ceftiofur resistant (n=76) and susceptible (n=45) strains of Bordetella bronchiseptica, Salmonella spp., Escherichia coli, and Pasteurella multocida were screened for the presence of these three genes. The resistant genes were detected in 70% (bla(TEM-1)), 68% (bla(CMY-2)) and 45% (ampC) of the resistant isolates and in 18% (bla(TEM-1)), 27% (bla(CMY-2)), and 36% (ampC) of the susceptible isolates. Results obtained in the present study showed widespread distribution of these three resistance genes in ceftiofur-resistant swine pathogens. It was also observed that more pathogens are acquiring these resistance genes.

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