Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Nov 15;587(Pt 22):5301-2.
doi: 10.1113/jphysiol.2009.182980.

A piece of the neocortical puzzle: the pyramid-Martinotti cell reciprocating principle

Affiliations
Review

A piece of the neocortical puzzle: the pyramid-Martinotti cell reciprocating principle

Kate A Buchanan et al. J Physiol. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1. A ubiquitous circuit motif in neocortex
In several neocortical regions, around 1 in 7 of nearby PC pairs are connected, but the disynaptic PC–MC–PC motif that mediates FDDI is more than twice as prevalent (Berger et al. 2009). Whereas PC–PC connections are depressing (red trace), the PC–MC pathway is facilitating (blue trace), so PCs must fire at high frequency to drive MCs and generate FDDI (Silberberg & Markram, 2007). Dashed lines: axons; continuous lines: dendrites; scalebars: 1 mV, 50 ms.

Comment on

References

    1. Berger TK, Perin R, Silberberg G, Markram H. J Physiol. 2009;587:5411–5425. - PMC - PubMed
    1. Hubel DH, Wiesel TN. J Physiol. 1962;160:106–154. - PMC - PubMed
    1. Kapfer C, Glickfeld LL, Atallah BV, Scanziani M. Nat Neurosci. 2007;10:743–753. - PMC - PubMed
    1. Murayama M, Perez-Garci E, Nevian T, Bock T, Senn W, Larkum ME. Nature. 2009;457:1137–1141. - PubMed
    1. Silberberg G, Markram H. Neuron. 2007;53:735–746. - PubMed

LinkOut - more resources