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. 2009 Nov 16;2(1):18.
doi: 10.1186/1757-2215-2-18.

Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis

Manuel García Manero  1 , Begoña Olartecoechea, Pedro Royo, Juan Luis Alcázar
Affiliations

Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis

Manuel García Manero et al. J Ovarian Res. .

Abstract

Objective: Thrombospondin-1 serum levels is correlate with pelvic pain in patients with ovarian endometriosis.

Patients: Thrombospondin-1 serum levels were prospectively analysed in 51 patients (group A asymptomatic patients or patients presenting mild dysmenorrhea and women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists among thrombospondin-1 serum levels and pelvic pain.

Results: From 56 patients, five cases were ultimately excluded, because the histological diagnosis was other than cystic ovarian endometriosis (2 teratomas and 3 haemorrhagic cysts). The mean thrombospondin-1 serum levels in group A was 256,69 pg/ml_+37,07 and in group B was 291,41 pg/ml + 35,59.

Conclusion: Pain symptoms in ovarian endometriosis is not correlated with thrombospondin-1 serum levels.

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