A PAR-SUMOnious mechanism of NEMO activation
- PMID: 19917242
- DOI: 10.1016/j.molcel.2009.10.022
A PAR-SUMOnious mechanism of NEMO activation
Abstract
In this issue of Molecular Cell, Stilmann et al. (2009) demonstrate a new mode of prosurvival NF-kappaB activation through the formation of a PARP-1-poly(ADP-ribose) signaling scaffold in response to DNA damage.
Comment on
-
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation.Mol Cell. 2009 Nov 13;36(3):365-78. doi: 10.1016/j.molcel.2009.09.032. Mol Cell. 2009. PMID: 19917246
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
