Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jan;38(Database issue):D331-5.
doi: 10.1093/nar/gkp1018. Epub 2009 Nov 17.

The Gene Ontology in 2010: extensions and refinements

Gene Ontology Consortium
Collaborators

The Gene Ontology in 2010: extensions and refinements

Gene Ontology Consortium. Nucleic Acids Res. 2010 Jan.

Abstract

The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO ontologies are expanding both in content and in structure. Several new relationship types have been introduced and used, along with existing relationships, to create links between and within the GO domains. These improve the representation of biology, facilitate querying, and allow GO developers to systematically check for and correct inconsistencies within the GO. Gene product annotation using GO continues to increase both in the number of total annotations and in species coverage. GO tools, such as OBO-Edit, an ontology-editing tool, and AmiGO, the GOC ontology browser, have seen major improvements in functionality, speed and ease of use.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
New intra- and inter-ontology relationships. (A) An example of a regulates link between two BP terms is pointed out by the arrow. An example of a part_of link between an MF term and a BP term is indicated by the circle. A regulates link between a BP term and an MF term is indicated by the triangle. (B) An example of a has_part link between two CC terms is pointed out by the arrow.
See this image and copyright information in PMC

References

    1. Torto-Alalibo T, Collmer CW, Gwinn-Giglio M. The Plant-Associated Microbe Gene Ontology (PAMGO) Consortium: community development of new Gene Ontology terms describing biological processes involved in microbe-host interactions. BMC Microbiol. 2009;9(Suppl. 1):S1. - PMC - PubMed
    1. Hill DP, Sitnikov D, Blake JA. Using gene ontology to study branching morphogenesis in mice. Dev. Biol. 2009;331:454.
    1. The Reference Genome Group of the Gene Ontology Consortium. The Gene Ontology's; Reference Genome Project: a unified framework for functional annotation across species. PLoS Comput. Biol. 2009;5:e1000431. - PMC - PubMed
    1. Mi H, Dong Q, Muruganujan A, Gaudet P, Lewis S, Thomas PD. PANTHER version 7: improved phylogenetic trees, orthologs, and collaboration with the Gene Ontology Consortium. Nucleic Acids Res. 2009;38:D204–D210. - PMC - PubMed
    1. Day-Richter J, Harris MA, Haendel M, Lewis S. OBO-Edit—an ontology editor for biologists. Bioinformatics. 2007;23:2198–2200. - PubMed

Publication types