Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Aug;14(3):501-6.
doi: 10.1007/s11030-009-9209-x. Epub 2009 Nov 17.

A mild and efficient synthesis of monofluorinated α-lactam pseudopeptides via a novel dehydrofluorination of Ugi products

Nianjin Liu  1 , Song Cao, Jingjing Wu, Li Shen, Jinlong Yu, Jian Zhang, Hui Li, Xuhong Qian
Affiliations

A mild and efficient synthesis of monofluorinated α-lactam pseudopeptides via a novel dehydrofluorination of Ugi products

Nianjin Liu et al. Mol Divers. 2010 Aug.

Abstract

Six novel monofluorinated α-lactam pseudopeptide derivatives were synthesized via Ugi reaction using gem-difluoromethylene-containing isocyanide as a key component, followed by dehydrofluorination of Ugi products in one pot without additional base.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Med Chem. 1993 Oct 15;36(21):3039-49 - PubMed
    1. Chem Rev. 2007 Nov;107(11):4437-92 - PubMed
    1. Curr Med Chem. 2004 May;11(9):1183-211 - PubMed
    1. J Pept Res. 2005 Nov;66(5):263-76 - PubMed
    1. J Org Chem. 2009 Feb 6;74(3):1377-80 - PubMed

Publication types

LinkOut - more resources