Sorting out endosomes in the WASH
- PMID: 19922862
- DOI: 10.1016/j.devcel.2009.10.019
Sorting out endosomes in the WASH
Erratum in
- Dev Cell. 2009 Dec;17(6):908
Abstract
Two new studies published in this issue of Developmental Cell by Derivery et al. and Gomez and Billadeau reveal that WASH (Wiskott-Aldrich syndrome protein and SCAR homolog) activates Arp2/3 on endosomes and plays a critical role in the fission of tubules that serve as transport intermediates during endosome sorting.
Comment on
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A FAM21-containing WASH complex regulates retromer-dependent sorting.Dev Cell. 2009 Nov;17(5):699-711. doi: 10.1016/j.devcel.2009.09.009. Dev Cell. 2009. PMID: 19922874 Free PMC article.
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The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.Dev Cell. 2009 Nov;17(5):712-23. doi: 10.1016/j.devcel.2009.09.010. Dev Cell. 2009. PMID: 19922875
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