Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
- PMID: 1992340
- DOI: 10.1038/349388a0
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
Abstract
Mutants of cdc2+ can disrupt the dependency of S phase on completion of the previous mitosis. By changing the state of p34cdc2 it is possible to reprogramme a cell from entering mitosis to undergoing S phase. This leads to the proposal that the cell cycle can be considered a p34cdc2 cycle, and has implications for the evolution of life cycles.
Comment in
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Cell biology. Remembrance of things past.Nature. 1991 Jan 31;349(6308):367-8. doi: 10.1038/349367a0. Nature. 1991. PMID: 1825129 No abstract available.
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