Vaccines against tularemia
- PMID: 19923904
- PMCID: PMC3132883
- DOI: 10.4161/hv.10297
Vaccines against tularemia
Abstract
Francisella tularensis is a Category A select agent for which vaccine and countermeasure development are a priority. In the past eight years, renewed interest in this pathogen has led to the generation of an enormous amount of new data on both the pathogen itself and its interaction with host cells. This information has fostered the development of various vaccine candidates including acellular subunit, killed whole cell and live attenuated. This review summarizes the progress and promise of these various candidates.
References
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- Aronova NV, Pavlovich NV. Phase variations of Francisella tularensis lipopolysaccharide in human infection and immunization. Zh Mikrobiol Epidemiol Immunobiol. 2005:8–12. - PubMed
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