Review
doi: 10.1111/j.1751-7133.2009.00108.x.
Heart diseases in mitochondrial encephalomyopathy, lactic acidosis, and stroke syndrome
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- PMID: 19925507
- DOI: 10.1111/j.1751-7133.2009.00108.x
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Review
Heart diseases in mitochondrial encephalomyopathy, lactic acidosis, and stroke syndrome
Congest Heart Fail.
2009 Nov-Dec.
Free article
Abstract
Mitochondrial encephalomyopathy, lactic acidosis, and stroke (MELAS) syndrome is a mitochondrial genetic disorder caused by a point mutation, resulting in the substitution of guanine for adenine at nucleotide 3243 (A3243G) of mitochondrial DNA. This disease is characterized by a multisystem disorder with variable manifestations. The authors review heart involvement in this disease.
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