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. 2009 Nov 20:27 Suppl 5:F35-9.
doi: 10.1016/j.vaccine.2009.08.087.

Rotavirus infection in hospitalized children and estimates of disease burden in Kyrgyzstan, 2005-2007

Elmira T Flem  1 , Kaliya T Kasymbekova, Kirsti Vainio, Jon Gentsch, Sabirjan T Abdikarimov, Roger I Glass, Joseph S Bresee
Affiliations

Rotavirus infection in hospitalized children and estimates of disease burden in Kyrgyzstan, 2005-2007

Elmira T Flem et al. Vaccine. .

Abstract

To estimate the rotavirus-associated burden in Kyrgyzstan, we conducted hospital surveillance among children <5 years old with diarrhoea during 2005-2007. Of 3756 children hospitalized with diarrhoea, 26% had rotavirus detected in stool samples by an enzyme immunoassay. The virus genotype G1P[8] was identified in 60% of 190 characterized samples from 2005 to 2006. The estimated risk for rotavirus hospitalization by age 5 years was 1 in 28 children. One quarter of all gastroenteritis hospitalizations in children <5 years old in Kyrgyzstan may be attributable to rotavirus. Rotavirus vaccination could be an important health intervention to reduce the burden of rotavirus gastroenteritis.

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