Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2009 Nov;27(9):1168.e3-7.
doi: 10.1016/j.ajem.2008.11.026.

Tricyclic antidepressant toxicity treated with massive sodium bicarbonate

Jessica E Pierog  1 , Kathleen E Kane, Bryan G Kane, J Ward Donovan, Tracey Helmick
Affiliations
Case Reports

Tricyclic antidepressant toxicity treated with massive sodium bicarbonate

Jessica E Pierog et al. Am J Emerg Med. 2009 Nov.

Abstract

Tricyclic antidepressant (TCA) morbitity is primarily due to cardiac arrhythmias and hypotension, which become more refractory to treatment as acidosis progresses (Ann Emerg Med. 1985;14:1-9; Clin Toxicol. 2007;45:203-233; Flomenbaum N, Goldfrank L, Hoffman R, et al. Goldfrank's toxicologic emergencies. 8th ed. McGraw-Hill Companies, Inc, 2006). Early recognition and aggressive treatment are necessary for patient survival.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

Publication types