Use of microRNA sponges to explore tissue-specific microRNA functions in vivo
- PMID: 19935840
- DOI: 10.1038/nmeth1209-873
Use of microRNA sponges to explore tissue-specific microRNA functions in vivo
Abstract
MicroRNA depletion by sequestration produces flexible hypomorphs that mimic mutants obtained by microRNA gene targeting.
Comment on
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Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.Nat Methods. 2009 Dec;6(12):897-903. doi: 10.1038/nmeth.1402. Epub 2009 Nov 15. Nat Methods. 2009. PMID: 19915559 Free PMC article.
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