The interaction of PVP complexes of gossypol and its derivatives with an artificial membrane lipid matrix
- PMID: 19936629
- PMCID: PMC6275622
- DOI: 10.2478/s11658-009-0037-x
The interaction of PVP complexes of gossypol and its derivatives with an artificial membrane lipid matrix
Abstract
In this paper, we present the results of a study on the membrane-active properties of gossypol, its derivatives and their polyvinylpyrrolidone complexes as assessed by differential scanning calorimetry and by the fluorescent probe method. The latter revealed the change in polarization of the incident radiation caused by the action of the polyphenol on the artificial membrane lipid matrix.
References
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- Lui G., Lyle K.C., Cao J. Trial of gossypol as a male contraceptive. In: Segal S.J., editor. Gossypol: a potential contraceptive for men. New York: Plenum Press; 1985. pp. 9–16.
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