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. 2010 Jan;17(1):199-201.
doi: 10.1128/CVI.00305-09. Epub 2009 Nov 25.

Long-term observation of subunit vaccine F1-rV270 against Yersinia pestis in mice

Zuyun Wang  1 , Lei Zhou, Zhizhen Qi, Qingwen Zhang, Ruixia Dai, Yonghai Yang, Baizhong Cui, Hu Wang, Ruifu Yang, Xiaoyi Wang
Affiliations

Long-term observation of subunit vaccine F1-rV270 against Yersinia pestis in mice

Zuyun Wang et al. Clin Vaccine Immunol. 2010 Jan.

Abstract

Long-term protection and antibody response for the subunit vaccine F1-rV270 were determined by using the mouse model. Antibodies to F1 and rV270 were still detectable over a period of 518 days. The complete protection against lethal challenge of Yersinia pestis could be achieved up to day 518 after primary immunization.

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Figures

FIG. 1.
FIG. 1.
Development of antibody titers to F1 and rV270 in female mice over a period of 77 days.
FIG. 2.
FIG. 2.
Development of antibody titers to F1 and rV270 in female mice over a period of 147 days.
FIG. 3.
FIG. 3.
Development of antibody titers to F1 and rV270 in female mice over a period of 539 days.
See this image and copyright information in PMC

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