Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009;10(11):114.
doi: 10.1186/gb-2009-10-11-114. Epub 2009 Nov 30.

Evolution, ecology and the engineered organism: lessons for synthetic biology

Affiliations

Evolution, ecology and the engineered organism: lessons for synthetic biology

Jeffrey M Skerker et al. Genome Biol. 2009.

Abstract

As the scope and complexity of synthetic biology grows, an understanding of evolution and ecology will be critical to its success.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Ecological forces drive evolution, which in turn influences ecologies. This cycle creates a diverse array of functions that can be used in synthetic designs. Individual functions may be combined and evolved in the laboratory to create new synthetic systems that may ultimately enter natural ecologies.

Similar articles

Cited by

References

    1. Driscoll CA, Macdonald DW, O'Brien SJ. From wild animals to domestic pets, an evolutionary view of domestication. Proc Natl Acad Sci USA. 2009;106(Suppl 1):9971–9978. doi: 10.1073/pnas.0901586106. - DOI - PMC - PubMed
    1. White S, Doebley J. Of genes and genomes and the origin of maize. Trends Genet. 1998;14:327–332. doi: 10.1016/S0168-9525(98)01524-8. - DOI - PubMed
    1. Bolotin A, Quinquis B, Renault P, Sorokin A, Ehrlich SD, Kulakauskas S, Lapidus A, Goltsman E, Mazur M, Pusch GD, Fonstein M, Overbeek R, Kyprides N, Purnelle B, Prozzi D, Ngui K, Masuy D, Hancy F, Burteau S, Boutry M, Delcour J, Goffeau A, Hols P. Complete sequence and comparative genome analysis of the dairy bacterium Streptococcus thermophilus. Nat Biotechnol. 2004;22:1554–1558. doi: 10.1038/nbt1034. - DOI - PMC - PubMed
    1. Nakao Y, Kanamori T, Itoh T, Kodama Y, Rainieri S, Nakamura N, Shimonaga T, Hattori M, Ashikari T. Genome sequence of the lager brewing yeast, an interspecies hybrid. DNA Res. 2009;16:115–129. doi: 10.1093/dnares/dsp003. - DOI - PMC - PubMed
    1. Lobban PE, Kaiser AD. Enzymatic end-to end joining of DNA molecules. J Mol Biol. 1973;78:453–471. doi: 10.1016/0022-2836(73)90468-3. - DOI - PubMed

Publication types