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. 2010 Aug;124(3):324-8.
doi: 10.1016/j.jad.2009.11.012. Epub 2009 Nov 25.

Self-reported cognitive problems predict employment trajectory in patients with bipolar I disorder

A M Gilbert  1 , T M Olino, P Houck, A Fagiolini, D J Kupfer, E Frank
Affiliations

Self-reported cognitive problems predict employment trajectory in patients with bipolar I disorder

A M Gilbert et al. J Affect Disord. 2010 Aug.

Abstract

Background: Cognitive impairment in bipolar disorder has been associated with poor functional outcomes. We examined the relation of self-reported cognitive problems to employment trajectory in patients diagnosed with bipolar I disorder.

Methods: 154 bipolar I disorder patients were followed for 15-43months at the Bipolar Disorders Center for Pennsylvanians. Using a multinomial logistic regression we examined predictors of employment group including self-reported cognitive problems, mood symptoms, education and age. Cognitive functioning was measured via 4 self-report items assessing memory/concentration at baseline and termination. Employment status was recorded at baseline and termination. Employment was categorized as working (full-time, part-time, homemaker, volunteer) or not working (leave of absence, disability, unemployed, no longer volunteering) at each time point. Patients were categorized as good stable, improving, worsening and poor stable.

Results: Baseline self-reported concentration problems and years of education significantly predicted employment trajectory.

Limitations: Post-hoc analyses of existing clinical data.

Conclusions: Self-reported concentration problems assessed in the context of specific areas of functioning may serve as a sensitive predictor of functional outcome in patients diagnosed with bipolar I disorder.

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