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Review
. 2010 Jan;15(1):103-7.
doi: 10.1007/s10741-009-9156-8.

Cardiomyopathy in Duchenne muscular dystrophy: pathogenesis and therapeutics

Abdallah Fayssoil  1 , Olivier Nardi, David Orlikowski, Djillali Annane
Affiliations
Review

Cardiomyopathy in Duchenne muscular dystrophy: pathogenesis and therapeutics

Abdallah Fayssoil et al. Heart Fail Rev. 2010 Jan.

Abstract

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by the absence of dystrophin, a sarcolemmal protein which links the cytoskeleton to the extracellular matrix by interacting with a large number of proteins. Heart failure is a classic complication of this disease. The authors review the pathogenesis and therapeutics of cardiac involvement in DMD.

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