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Review
. 2009 Dec;36(4):807-34, vi.
doi: 10.1016/j.clp.2009.07.007.

Advances in near-infrared spectroscopy to study the brain of the preterm and term neonate

Martin Wolf  1 , Gorm Greisen
Affiliations
Review

Advances in near-infrared spectroscopy to study the brain of the preterm and term neonate

Martin Wolf et al. Clin Perinatol. 2009 Dec.

Abstract

This article reviews tissue oximetry and imaging to study the preterm and newborn infant brain by near-infrared spectroscopy. These two technologies are now advanced; nearly 100 reports on their use in newborn infants have been published, and commercial instruments are available. The precision of oximetry, however, is a limitation for its clinical use of assessing cerebral oxygenation. Imaging of brain function needs very well defined protocols for sensory stimulation as well as signal analysis to provide meaningful results.

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