An acid-sensing channel sows fear and panic
- PMID: 19945375
- DOI: 10.1016/j.cell.2009.11.008
An acid-sensing channel sows fear and panic
Abstract
The amygdala is a brain region that coordinates fear responses to a variety of threats. Ziemann et al. (2009) now show that acid-sensing channels in the amygdala mediate fear responses that accompany inhalation of carbon dioxide, suggesting that aberrant chemosensation may underlie anxiety disorders associated with a fear of suffocation.
Comment on
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The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior.Cell. 2009 Nov 25;139(5):1012-21. doi: 10.1016/j.cell.2009.10.029. Cell. 2009. PMID: 19945383 Free PMC article.
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