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Multicenter Study
. 2010 Aug;69(8):1572-3.
doi: 10.1136/ard.2009.122887. Epub 2009 Nov 27.

Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population

Stephen Eyre, Anne Hinks, Edward Flynn, Paul Martin, Anthony G Wilson, James R Maxwell, Ann W Morgan, Paul Emery, Sophia Steer, Lynne J Hocking, David M Reid, Pille Harrison, Paul Wordsworth, Wendy Thomson, Jane Worthington, Anne Barton
Multicenter Study

Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population

Stephen Eyre et al. Ann Rheum Dis. 2010 Aug.

Erratum in

  • Ann Rheum Dis. 2011 Aug;70(8):1519
No abstract available

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Figures

Figure 1
Figure 1
Meta-analysis of current UK data with previous data. US and US/Canadian allele counts from Gregersen et al. Combined p value=1.53×10−17. OR, odds ratio.
See this image and copyright information in PMC

References

    1. Barton A, Worthington J. Genetic susceptibility to rheumatoid arthritis: an emerging picture. Arthritis Rheum 2009;61:1441–6 - PubMed
    1. Plenge RM, Seielstad M, Padyukov L, et al. TRAF1-C5 as a risk locus for rheumatoid arthritis—a genomewide study. N Engl J Med 2007;357:1199–209 - PMC - PubMed
    1. Gregersen PK, Amos CI, Lee AT, et al. REL, encoding a member of the NF-kappa B family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet 2009;41:820–3 - PMC - PubMed
    1. Thomson W, Barton A, Ke X, et al. Rheumatoid arthritis association at 6q23. Nat Genet 2007;39:1431–3 - PMC - PubMed
    1. Barton A, Thomson W, Ke X, et al. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet 2008;40:1156–9 - PMC - PubMed