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. 2009 Oct 29:2:174.
doi: 10.1186/1757-1626-2-174.

Invasive ductal carcinoma within fibroadenoma: a case report

Lumturije H Gashi-Luci  1 , Rinë A Limani, Fisnik I Kurshumliu
Affiliations

Invasive ductal carcinoma within fibroadenoma: a case report

Lumturije H Gashi-Luci et al. Cases J. .

Abstract

Introduction: Fibroadenoma is the most common benign tumor of the female breast with the highest incidence before age 30. Fibroadenoma may be associated with fibrocystic changes, proliferative epithelial changes, and extremely rarely, with non-invasive and invasive cancer.

Case presentation: We present a rare case of a 39 years old female with invasive ductal carcinoma arising within fibroadenoma.

Conclusion: There is a low percentage of fibroadenomas harboring carcinoma; however, all breast lumps should be seriously managed; extirpation and histological examination is recommended.

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Figures

Figure 1
Figure 1
Ultrasonography. Partially well defined mass consisted of heterogenous hypoechoic foci.
Figure 2
Figure 2
Mammography. Solitary lesion with variable density.
Figure 3
Figure 3
Ductal carcinoma in situ with focal comedo necrosis and fibroadenoma. Fibroadenoma In the left hand of the field (×10; H&E stain).
Figure 4
Figure 4
Infiltrating islands of malignant ductal epithelial cells and fibroadenoma. Fibroadenoma in the lower left corner of the field (×10 H&E stain).
Figure 5
Figure 5
Infiltrative ductal carcinoma with inflammatory cells in the stroma (×20; H&E stain).
See this image and copyright information in PMC

References

    1. Cheatle GL, Cutler M. Tumours of the breast. Their pathology, symptoms, diagnosis and treatment. London: Edward Arnoled & CO; 1931. pp. 483–4.
    1. Azzopardi JG. In: Major problems in Pathology. Bennigton JC, editor. Edinburgh: WB Saunders Company Ltd; 1979. Problems in Breast pathology. - PubMed
    1. Diaz NM, Palmer JO, McDivitt RW. Carcinoma arising within fibroadenomas of the breast; a clinicopathologic study of 105 patients. AM J Clin Pathol. 1991;95:614–22. - PubMed
    1. Buzanowski-Konakry K, Harrison EG Jr, Payne WS. Lobular carcinoma arising in fibroadenoma of the breast. Cancer. 1975;35:450–6. doi: 10.1002/1097-0142(197502)35:2<450::AID-CNCR2820350223>3.0.CO;2-R. - DOI - PubMed
    1. Ozello L, Gump FE. The management of patients with carcinomas in fibroadenomatus tumours of breast. Surg Gynecol Obstet. 1985;160:99–104. - PubMed

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