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Editorial
. 2009 Dec 15;8(24):4003-4.
doi: 10.4161/cc.8.24.10146. Epub 2009 Dec 21.

Arginine methylation as a molecular signature of the Piwi small RNA pathway

Editorial

Arginine methylation as a molecular signature of the Piwi small RNA pathway

Vasily V Vagin et al. Cell Cycle. .
No abstract available

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Figures

Figure 1
Figure 1
(A) The structure of Tudor proteins and their interaction with PIWIs. KH is RNA binding motif; TM is transmembrane motif; DEXDC, HELICc and HA2 are RNA helicase motifs; MYND and RING are motifs with unknown functions. (B) The proposed model for TDRD1 function in assembly of nuage and association of Piwi proteins for the ping-pong cycle. Methylated arginines of Piwi proteins (MILI and MIWI2), as well as those of other proteins such as MVH, interact with different Tudor domains of TDRD1. (C) Expression of PIWI and Tudor family members and piRNA during male germline development in mouse.

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