Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2009 Sep;50(9):963-7.

Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog

Aubrey A Webb  1 , Chantal McMillan, Cheryl L Cullen, Sarah E Boston, Julie Turnbull, Berge A Minassian
Affiliations
Case Reports

Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog

Aubrey A Webb et al. Can Vet J. 2009 Sep.

Abstract
in English, French

An 8-year-old, castrated male, miniature wire-haired dachshund was presented with a 4-month history of intermittent facial twitching (myoclonus). The myoclonic episodes progressed over a 16-month period. Generalized seizure activity was infrequent. Clinical examination revealed visually stimulated myoclonus. Response to therapy with antiepileptic drugs was equivocal. Genetic testing identified the dog as being affected by Lafora disease.

Maladie de Lafora comme cause d’attaques myocloniques exacerbées chez un chien. Un Dachsund miniature à poils raides mâle castré âgé de 8 ans a été présenté avec une anamnèse de 4 mois de secousses musculaires faciales intermittentes (myoclonie). Les épisodes myocloniques ont progressé pendant une période de 16 mois. L’activité épileptique généralisée était peu fréquente. Un examen clinique a révélé la myoclonie à stimulation visuelle. La réponse à la thérapie à l’aide de médicaments antiépileptiques a été équivoque. Un dépistage génétique a identifié le chien comme étant atteint par la maladie de Lafora.

(Traduit par Isabelle Vallières)

PubMed Disclaimer

Figures

Figure 1
Figure 1
Cross section T2-weighted MR image of the dog’s brain. Note the dilatation of the lateral ventricles.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Podell M. Tremor, fasciculations, and movement disorders. Vet Clin North Am Small Anim Pract. 2004;34:1435–1452. - PubMed
    1. Faught E. Clinical presentations and phenomenology of myoclonus. Epilepsia. 2003;44 (Suppl 11):7–12. - PubMed
    1. de Lahunta A, Glass E. Upper motor neuron. In: de Lahunta A, Glass E, editors. Veterinary Neuroanatomy and Clinical Neurology. St Louis: Saunders/Elsevier; 2009. pp. 192–220.
    1. Fahn S. Overview, history, and classification of myoclonus. Adv Neurol. 2002;89:13–17. - PubMed
    1. Trepanier LA, Van SA, Schwark WS, Carrillo J. Therapeutic serum drug concentrations in epileptic dogs treated with potassium bromide alone or in combination with other anticonvulsants: 122 cases (1992–1996) J Am Vet Med Assoc. 1998;213:1449–1453. - PubMed

Publication types

Substances

LinkOut - more resources