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Case Reports
. 2009 Sep;50(9):963-7.

Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog

Aubrey A Webb  1 , Chantal McMillan, Cheryl L Cullen, Sarah E Boston, Julie Turnbull, Berge A Minassian
Affiliations
Case Reports

Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog

Aubrey A Webb et al. Can Vet J. 2009 Sep.

Abstract
in English, French

An 8-year-old, castrated male, miniature wire-haired dachshund was presented with a 4-month history of intermittent facial twitching (myoclonus). The myoclonic episodes progressed over a 16-month period. Generalized seizure activity was infrequent. Clinical examination revealed visually stimulated myoclonus. Response to therapy with antiepileptic drugs was equivocal. Genetic testing identified the dog as being affected by Lafora disease.

Maladie de Lafora comme cause d’attaques myocloniques exacerbées chez un chien. Un Dachsund miniature à poils raides mâle castré âgé de 8 ans a été présenté avec une anamnèse de 4 mois de secousses musculaires faciales intermittentes (myoclonie). Les épisodes myocloniques ont progressé pendant une période de 16 mois. L’activité épileptique généralisée était peu fréquente. Un examen clinique a révélé la myoclonie à stimulation visuelle. La réponse à la thérapie à l’aide de médicaments antiépileptiques a été équivoque. Un dépistage génétique a identifié le chien comme étant atteint par la maladie de Lafora.

(Traduit par Isabelle Vallières)

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Figures

Figure 1
Figure 1
Cross section T2-weighted MR image of the dog’s brain. Note the dilatation of the lateral ventricles.
See this image and copyright information in PMC

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