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. 2009 Aug;22(4):340-4.
doi: 10.1016/S0895-3988(09)60065-9.

Unusual patterns of neural tube defects in a high risk region of northern China

Gong Chen  1 , Li-Jun Pei, Jian Huang, Xin-Ming Song, Liang-Ming Lin, Xue Gu, Jian-Xin Wu, Fang Wang, Ji-Lei Wu, Jia-Peng Chen, Ju-Fen Liu, Ruo-Lei Xin, Ting Zhang, Xiao-Ying Zheng
Affiliations

Unusual patterns of neural tube defects in a high risk region of northern China

Gong Chen et al. Biomed Environ Sci. 2009 Aug.

Abstract

Objective: To study the prevalence of different types of neural tube defects (NTDs) in Luliang Prefecture, Shanxi province, where the prevalence of NTDs is unusually high and the correlation between NTDs prevalence and patterns.

Methods: A surveillance population-based birth defects was performed in Luliang Prefecture, Shanxi province.

Results: The results of our study showed that the prevalence of NTDs was 2-fold higher in Luliang Prefecture than in other areas of Shanxi province. Unusual patterns of NTDs were found, however, multiple NTDs were relatively common in Luliang Prefecture, accounting for over 13% of all NTDs cases in China.

Conclusion: The prevalence of NTDs is associated with its patterns.

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