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. 2010 Jan 1;50(1):80-3.
doi: 10.1086/648726.

Miltefosine treatment of Leishmania major infection: an observational study involving Dutch military personnel returning from northern Afghanistan

P P A M van Thiel  1 , T Leenstra, P A Kager, H J de Vries, M van Vugt, W F van der Meide, A Bart, J E Zeegelaar, A van der Sluis, H D F H Schallig, T van Gool, W R Faber, P J de Vries
Affiliations

Miltefosine treatment of Leishmania major infection: an observational study involving Dutch military personnel returning from northern Afghanistan

P P A M van Thiel et al. Clin Infect Dis. .

Abstract

In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSb(v)), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSb(v), and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients.

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