Preview. SKPing a hurdle: Sox2 and adult dermal stem cells
- PMID: 19951681
- DOI: 10.1016/j.stem.2009.11.010
Preview. SKPing a hurdle: Sox2 and adult dermal stem cells
Abstract
In this issue of Cell Stem Cell, Biernaskie et al. (2009) demonstrate that a specific subpopulation of dermal papilla fibroblasts, marked by Sox2 expression, displays properties of adult stem cells, including serial hair follicle initiation, dermal cell differentiation, and skin-derived precursor production.
Comment on
-
SKPs derive from hair follicle precursors and exhibit properties of adult dermal stem cells.Cell Stem Cell. 2009 Dec 4;5(6):610-23. doi: 10.1016/j.stem.2009.10.019. Cell Stem Cell. 2009. PMID: 19951689 Free PMC article.
Similar articles
-
Dermal papilla cells derived from beard hair follicles secrete more stem cell factor (SCF) in culture than scalp cells or dermal fibroblasts.Biochem Biophys Res Commun. 1996 May 15;222(2):401-5. doi: 10.1006/bbrc.1996.0756. Biochem Biophys Res Commun. 1996. PMID: 8670217
-
Differences in hair follicle dermal papilla volume are due to extracellular matrix volume and cell number: implications for the control of hair follicle size and androgen responses.J Invest Dermatol. 1999 Dec;113(6):873-7. doi: 10.1046/j.1523-1747.1999.00797.x. J Invest Dermatol. 1999. PMID: 10594724
-
Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells.Cell Tissue Res. 2014 Feb;355(2):463-70. doi: 10.1007/s00441-013-1745-0. Epub 2013 Nov 20. Cell Tissue Res. 2014. PMID: 24253465
-
Do androgens influence hair growth by altering the paracrine factors secreted by dermal papilla cells?Eur J Dermatol. 2001 Jul-Aug;11(4):315-20. Eur J Dermatol. 2001. PMID: 11399537 Review.
-
[A review of studies on hair follicle dermal sheath cells].Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2007 Jun;24(3):694-6. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2007. PMID: 17713291 Review. Chinese.
Cited by
-
Induction of osteoblastic differentiation of neural crest-derived stem cells from hair follicles.PLoS One. 2017 Apr 6;12(4):e0174940. doi: 10.1371/journal.pone.0174940. eCollection 2017. PLoS One. 2017. PMID: 28384239 Free PMC article.
-
Therapeutic Potential of Skin Stem Cells and Cells of Skin Origin: Effects of Botanical Drugs Derived from Traditional Medicine.Stem Cell Rev Rep. 2022 Aug;18(6):1986-2001. doi: 10.1007/s12015-022-10388-y. Epub 2022 Jun 1. Stem Cell Rev Rep. 2022. PMID: 35648312 Review.
-
Stem cell niches for skin regeneration.Int J Biomater. 2012;2012:926059. doi: 10.1155/2012/926059. Epub 2012 Jun 3. Int J Biomater. 2012. PMID: 22701121 Free PMC article.
-
Molecular profiling of skin cells identifies distinct cellular signatures in radiation-induced skin injury across various stages in the murine dataset.Exp Hematol Oncol. 2025 Feb 25;14(1):18. doi: 10.1186/s40164-025-00596-w. Exp Hematol Oncol. 2025. PMID: 40001256 Free PMC article.
-
A new isolation method of human limbal progenitor cells by maintaining close association with their niche cells.Tissue Eng Part C Methods. 2011 May;17(5):537-48. doi: 10.1089/ten.TEC.2010.0609. Epub 2011 Feb 14. Tissue Eng Part C Methods. 2011. PMID: 21175372 Free PMC article.
Publication types
Grants and funding
LinkOut - more resources
Full Text Sources