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. 2009 Oct;4(1):59-65.
doi: 10.1186/1479-7364-4-1-59.

The cytochrome p450 homepage

David R Nelson  1
Affiliations

The cytochrome p450 homepage

David R Nelson. Hum Genomics. 2009 Oct.

Abstract

The Cytochrome P450 Homepage is a universal resource for nomenclature and sequence information on cytochrome P450 ( CYP ) genes. The site has been in continuous operation since February 1995. Currently, naming information for 11,512 CYPs are available on the web pages. The P450 sequences are manually curated by David Nelson, and the nomenclature system conforms to an evolutionary scheme such that members of CYP families and subfamilies share common ancestors. The organisation and content of the Homepage are described.

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Figures

Figure 1
Figure 1
The top of Cytochrome P450 Homepage.
Figure 2
Figure 2
The top part of the Human P450 Master Table.
See this image and copyright information in PMC

References

    1. Nelson DR, Kamataki T, Waxman DJ, Guengerich FP. et al. The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes and nomenclature. DNA Cell Biol. 1993;12:1–51. doi: 10.1089/dna.1993.12.1. - DOI - PubMed
    1. Nebert DW, Gonzalez FJ. P450 genes: Structure, evolution, and regulation. Annu Rev Biochem. 1987;56:945–993. doi: 10.1146/annurev.bi.56.070187.004501. - DOI - PubMed
    1. Nebert DW, Nelson DR, Adesnik MA, Coon MJ. et al. The P450 superfamily: Update on listing of all genes and recommended nomenclature of the chromosomal loci. DNA. 1989;8:1–13. doi: 10.1089/dna.1.1989.8.1. - DOI - PubMed
    1. Nebert DW, Nelson DR, Coon MJ, Estabrook RW. et al. The P450 superfamily: Update on new sequences, gene mapping and recommended nomenclature. DNA Cell Biol. 1991;10:1–14. doi: 10.1089/dna.1991.10.1. - DOI - PubMed
    1. Fischer M, Knoll M, Sirim D, Wagner F. et al. The Cytochrome P450 Engineering Database: A navigation and prediction tool for the cytochrome P450 protein family. Bioinformatics. 2007;23:2015–2017. doi: 10.1093/bioinformatics/btm268. - DOI - PubMed

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