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. 2010 Aug;56(4):280-3.
doi: 10.1093/tropej/fmp115. Epub 2009 Dec 1.

Immune reconstitution inflammatory syndrome due to Mycobacterium bovis Bacillus Calmette-Guerin in infants receiving highly active antiretroviral therapy: a call for universal perinatal rapid HIV testing prior to administration of BCG immunization of neonates

Alexander Koppel  1 , Jose Leonardo-Guerrero, Sarah Rives, Noemí Paniagua-Torres, Celine Sparrow, Consuelo M Beck-Sagué
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Immune reconstitution inflammatory syndrome due to Mycobacterium bovis Bacillus Calmette-Guerin in infants receiving highly active antiretroviral therapy: a call for universal perinatal rapid HIV testing prior to administration of BCG immunization of neonates

Alexander Koppel et al. J Trop Pediatr. 2010 Aug.

Abstract

The evidence behind the World Health Organization guidelines that BCG vaccination should not be used in HIV-infected children is compelling. We report three cases of severe BCG-associated immune reconstitution syndrome in HIV-infected infants and describe measures available in developing countries that prevent inadvertent BCG immunization in these infants.

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