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Comparative Study
. 2009 Dec;124(6):2072-2075.
doi: 10.1097/PRS.0b013e3181bcefc4.

Intracranial volumes in a large series of healthy children

Mehul R Kamdar  1 , R Alex Gomez, Jeffrey A Ascherman
Affiliations
Comparative Study

Intracranial volumes in a large series of healthy children

Mehul R Kamdar et al. Plast Reconstr Surg. 2009 Dec.

Abstract

Background: Craniosynostosis alters the normal growth of the infant skull and can influence intracranial pressure and intracranial volume. The purpose of this study was to measure intracranial volumes in a large series of healthy children to serve as a reference for further studies exploring the impact of craniosynostosis and vault remodeling on intracranial growth.

Methods: A total of 123 children were included in this study from a retrospective review of pediatric emergency room visits for evaluation of head trauma where a head computed tomography scan was performed. Intracranial volumes were obtained using a semiautomated image segmentation technique and volume-rendering software.

Results: Volume measurements were obtained and plotted against age, and a best fit curve approximation was derived. In this study of healthy children, intracranial volume doubled by 9 months of age and tripled by 6 years of age.

Conclusions: This large study contributes to the existing data demonstrating intracranial volumes in healthy children up to 6 years of age. These data can be used by clinicians as a reference in the assessment of a child presenting with cranial dysmorphology.

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