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. 2010 Mar;29(3):269-71.
doi: 10.1097/INF.0b013e3181c15977.

Reactogenicity and immunogenicity of combined Haemophilus influenzae type b-meningococcal serogroup C conjugate vaccine booster dose coadministered with measles, mumps, and rubella vaccine

Alfonso Carmona  1 , Mariano Miranda, Francisco Barrio, Ana De Vicente, Josep Mares, Eulalia Muñoz, Javier Diez-Delgado, Angeles Alonso, Francisco Giménez-Sánchez, José Merino, Pilar García-Corbeira, Gudrun Maechler, Dominique Boutriau; Spanish 103954 Study Group
Collaborators, Affiliations

Reactogenicity and immunogenicity of combined Haemophilus influenzae type b-meningococcal serogroup C conjugate vaccine booster dose coadministered with measles, mumps, and rubella vaccine

Alfonso Carmona et al. Pediatr Infect Dis J. 2010 Mar.

Abstract

A booster dose of Haemophilus influenzae type b-Neisseria meningitidis serogroup C conjugate (Hib-MenC-TT) vaccine simultaneously administered with measles, mumps, and rubella (MMR) vaccine in 13- to 14-month-old Spanish toddlers, primed with 3 doses of a combined Diphteria-Tetanus-Acellular Pertusis DTPa-Hib-containing vaccine and a MenC-CRM197 conjugate vaccine, had a good reactogenicity profile and induced similar Hib and MenC booster responses and MMR seropositivity rates as the vaccines given alone.

Trial registration: ClinicalTrials.gov NCT00263653.

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