Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2009 Dec;15(8):399-401.
doi: 10.1097/RHU.0b013e3181c377ea.

A case of localized scleroderma in a sculptor and his wife

Richard Bakst  1 , Carrie Kovarik, Victoria P Werth
Affiliations
Case Reports

A case of localized scleroderma in a sculptor and his wife

Richard Bakst et al. J Clin Rheumatol. 2009 Dec.

Abstract

The etiology of localized scleroderma is unknown, and its pathogenetic relationship to its systemic counterpart is unclear. Environmental exposures, notably to silica dust, have long been suspected in the pathogenesis of the disorder. However, its relationship to the localized variant has not been well described. Here we present 2 cases of localized scleroderma in a sculptor and his wife who have extensive exposure to silica dust.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflict of interest to disclose. There were no funding sources for this work. This case is not currently submitted elsewhere; however, it was presented at a scientific meeting.

Figures

FIGURE 1
FIGURE 1
Sculptor: (A) Indurated skin on chest; (B) Medallion-sized, indurated, yellow plaque on right axilla.
FIGURE 2
FIGURE 2
Wife: Faint hyperpigmented patches on the dorsum of arm.
FIGURE 3
FIGURE 3
(A) The biopsy shows diffusely thickened and eosinophilic collagen bundles within the reticular dermis, as well as a superficial and deep, perivascular, and periadenexal lymphoplasmacytic infiltrate with scattered histiocytes; (B) The diffusely thickened and eosinophilic collagen bundles are more pronounced upon closer examination.
See this image and copyright information in PMC

References

    1. Peterson LS, Nelson AM, Su WP. Classification of morphea (localized scleroderma) Mayo Clin Proc. 1995;70:1068–76. - PubMed
    1. Jablonska S. Familial occurrence of scleroderma. J Eur Acad Dermatol Venereol. 2001;15:9–10. - PubMed
    1. Weide B, Walz T, Garbe C. Is morphoea caused by Borrelia burgdorferi? A review. Br J Dermatol. 2000;142:636–44. - PubMed
    1. Del Rosso A, Pignone A, Giacomelli R, Cerinic MM. Familial scleroderma: do environmental factors, genes and microchimerism share the same relevance. J Eur Acad Dermatol Venereol. 2001;15:11–4. - PubMed
    1. Haustein UF, Ziegler V. Environmentally induced systemic-sclerosis-like disorders. Int J Dermatol. 1985;24:147–51. - PubMed

Publication types

Substances