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Case Reports
. 2009:2009:942301.
doi: 10.1155/2009/942301. Epub 2009 May 19.

Clinical commentary: obstetric and respiratory management of pregnancy with severe spinal muscular atrophy

Daniel Flunt  1 , Natasha Andreadis, Collette Menadue, Alec W Welsh
Affiliations
Case Reports

Clinical commentary: obstetric and respiratory management of pregnancy with severe spinal muscular atrophy

Daniel Flunt et al. Obstet Gynecol Int. 2009.

Abstract

We present a combined obstetric and respiratory perspective on two pregnancies for a woman with severe Type 2 Spinal Muscular Atrophy (SMA). Our patient had the lowest prepregnancy weight (20 kg) and vital capacity of 0.34 L (VC 11% predicted) yet to be reported in the sparse literature on pregnancy with SMA. She delivered two live healthy infants via planned caesarean section without pregnancy or neonatal complication. We describe the respiratory and obstetric management techniques used for a pregnancy with this degree of respiratory compromise.

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Figures

Figure 1
Figure 1
Vital capacity (VC) (solid line) and room air oxygen saturations (SpO2) (dashed line) measured at week from gestation for (a) the first and (b) the second pregnancies.
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