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. 2009:2009:4281-2.
doi: 10.1109/IEMBS.2009.5332708.

Multi-scale modeling of excitation-contraction coupling in the normal and failing heart

Roy C P Kerckhoffs  1 , Stuart G Campbell, Sarah N Flaim, Elliot J Howard, Jazmin Sierra-Aguado, L J Mulligan, Andrew D McCulloch
Affiliations

Multi-scale modeling of excitation-contraction coupling in the normal and failing heart

Roy C P Kerckhoffs et al. Annu Int Conf IEEE Eng Med Biol Soc. 2009.

Abstract

Here we describe new computational models of cardiac electromechanics starting from the cellular scale and building to the tissue, organ and system scales. We summarize application to human genetic diseases (LQT1 and LQT3) and to modeling of congestive heart failure.

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Figures

Fig. 1
Fig. 1
Schematic of integrated excitation-contraction coupling model of the cardiac myocyte.
See this image and copyright information in PMC

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