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. 2009:2009:4566-8.
doi: 10.1109/IEMBS.2009.5332695.

Preliminary 6 month results from the Argus II epiretinal prosthesis feasibility study

Mark S Humayun  1 , Jessy D Dorn, Ashish K Ahuja, Avi Caspi, Eugene Filley, Gislin Dagnelie, Joël Salzmann, Arturo Santos, Jacque Duncan, Lyndon daCruz, Saddek Mohand-Said, Dean Eliott, Matthew J McMahon, Robert J Greenberg
Affiliations

Preliminary 6 month results from the Argus II epiretinal prosthesis feasibility study

Mark S Humayun et al. Annu Int Conf IEEE Eng Med Biol Soc. 2009.

Abstract

The Argus II 60 channel epiretinal prosthesis has been developed in order to provide partial restoration of vision to subjects blinded from outer retinal degenerative disease. To date the device has been implanted in 21 subjects as part of a feasibility study. In 6 month post-implantation door finding and line tracking orientation and mobility testing, subjects have shown improvements of 86% and 73%, respectively, for system on vs. system off. In high-contrast Square Localization tests using a touch screen monitor 87% of tested subjects performed significantly better with the system on compared with off. These preliminary results show that the Argus II system provides some functional vision to blind subjects.

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Figures

Figure 1
Figure 1
Photographs showing a subject performing the door finding (left) and line tracking (right) tasks.
Figure 2
Figure 2
Photographs showing a subject performing the Square Localization (left) and Direction of Motion (right) tests.
Figure 3
Figure 3
Average success rate measured at baseline, 3 months post-op, and 6 months post-op for the door finding task (n=17).
Figure 4
Figure 4
Average success rate measured at baseline, 3 months post-op, and 6 months post-op for the line tracking task (n=17).
Figure 5
Figure 5
Mean distance from square center (in pixels) for each subject with the system on (dark circles) and off (light circles). Cases in which there is a significant difference between the means in these two cases is demarcated with a star.
See this image and copyright information in PMC

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