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Case Reports
. 1991 Jan;86(3):279-82.
doi: 10.1007/BF00202409.

Synaptonemal complex analysis in a human male carrier of a 4;6 translocation: heterosynapsis without previous homosynapsis

A de Perdigo  1 , O Gabriel-Robez, C Ratomponirina, Y Rumpler
Affiliations
Case Reports

Synaptonemal complex analysis in a human male carrier of a 4;6 translocation: heterosynapsis without previous homosynapsis

A de Perdigo et al. Hum Genet. 1991 Jan.

Abstract

Silver-stained synaptonemal complexes in surface-spread pachytene nuclei from a man, heterozygous for a reciprocal translocation, were analysed by electron microscopy. Contrary to the classically expected cross-shaped configuration, extensive non-homologous pairings were observed with asymmetrical association in the lateral elements of the non-homologous arms of the quadrivalents. A possible role of the heterosynapsis in reproductive failure is discussed.

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References

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