Blood stage-induced Plasmodium brasilianum infection in the squirrel monkey induces antibodies which react with the circumsporozoite protein
- PMID: 1997421
- PMCID: PMC258386
- DOI: 10.1128/iai.59.3.1180-1182.1991
Blood stage-induced Plasmodium brasilianum infection in the squirrel monkey induces antibodies which react with the circumsporozoite protein
Abstract
A blood stage-induced P. brasilianum infection in a naive squirrel monkey induced antibodies which reacted with the circumsporozoite protein of the parasite. Titers increased with duration of infection and persisted for 3 months after cure. In an immunoblot, these antibodies detected two polypeptides with molecular weights identical to those of the circumsporozoite protein and its precursor.
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