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. 1991 Feb;86(4):369-70.
doi: 10.1007/BF00201836.

Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population

S Olschwang  1 , P Laurent-Puig, A Vassal, R J Salmon, G Thomas
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Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population

S Olschwang et al. Hum Genet. 1991 Feb.

Abstract

We describe a simple method for characterizing a frequent polymorphism (that substitutes an arginine for a proline) in the coding sequence of the Tp53 gene in patients with colonic cancer and in a control population. We could find no evidence that this polymorphism is associated with a marked predisposition to colorectal cancer.

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References

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