Genes for 7S RNAs can replace the gene for 4.5S RNA in growth of Escherichia coli
- PMID: 1999396
- PMCID: PMC207341
- DOI: 10.1128/jb.173.5.1835-1837.1991
Genes for 7S RNAs can replace the gene for 4.5S RNA in growth of Escherichia coli
Abstract
4.5S RNAs of eubacteria and 7S RNAs of archaebacteria and eukaryotes exist in a hairpin conformation. The apex of this hairpin displays structural and sequence similarities among both 4.5S and 7S RNAs. Furthermore, a hyphenated sequence of 16 nucleotides is conserved in all eubacterial 4.5S RNAs examined. In this article I report that 7S RNAs that contain this 16-nucleotide sequence are able to replace 4.5S RNAs and permit growth of Escherichia coli.
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