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Case Reports
. 2009 Oct;109(5):629-32.
doi: 10.1080/00015458.2009.11680502.

Co-existence of gastrointestinal stromal tumors with malign epithelial tumors: a report of two cases

O Firat  1 , P Yazici, O Makay, A Aydin, M Tuncyurek, S Ersin, A Guler
Affiliations
Case Reports

Co-existence of gastrointestinal stromal tumors with malign epithelial tumors: a report of two cases

O Firat et al. Acta Chir Belg. 2009 Oct.

Abstract

Aim: To emphasize the importance of a detailed observation for incidental simultaneous tumoral masses during surgery for gastrointestinal stromal tumors (GISTs) at any location in the gastrointestinal system.

Case presentations: Case 1: a 39-year-old female patient with an esophageal squamous cell carcinoma and a synchronous small intestinal GIST discovered incidentally during esophagectomy. Case 2: a 73-year-old female patient with a gastric GIST and a synchronous colorectal cancer detected incidentally during gastrectomy. In both cases, immunohistochemical examinations of the resected specimens confirmed the coexistences of GISTs and epithelial malignancies.

Conclusion: The coexistences of GISTs with epithelial tumors have been increasing in recent years. In any case of a GIST or gastrointestinal adenocarcinoma, the surgeon should be alert to recognize a possible coexistent tumor with different histological origin.

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