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Case Reports
. 2009 Dec 8;73(23):2037-9.
doi: 10.1212/WNL.0b013e3181c55ee7.

Idiopathic eosinophilic meningoencephalomyelitis following Well syndrome

Peter E Turkeltaub  1 , Miguel A Guzman, Edward B Lee, Steven L Galetta
Affiliations
Case Reports

Idiopathic eosinophilic meningoencephalomyelitis following Well syndrome

Peter E Turkeltaub et al. Neurology. .
No abstract available

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Figures

None
Figure Histopathology of eosinophilic cellulitis and meningoencephalitis (A, B) Skin biopsy showed a dermal eosinophilic infiltrate associated with necrotic collagen (so-called “flame figures,” shown in inset) consistent with Well syndrome. Stains for microorganisms were negative. (C) Right temporal leptomeningeal and neocortical biopsy revealed a mixed inflammatory infiltrate comprised of lymphocytes, eosinophils (see inset), plasma cells, and macrophages with a prominent perivascular distribution. (D) The inflammatory infiltrate was associated with a florid astrocytic gliosis, highlighted by glial fibrillary acid protein staining (inset). Detailed staining did not reveal evidence for an infectious cause or malignancy. Scale bars: 500 μm (A), 62.5 μm (B, D), 125 μm (C).
See this image and copyright information in PMC

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