Ethical issues in the difference between placebo-controlled and active-controlled trials

Affiliations

Comment

Carlo Petrini. Am J Bioeth. 2009 Sep.

. 2009 Sep;9(9):56-8.

doi: 10.1080/15265160903098606.

¹ Bioethics Unit, Office of the President, Istituto Superiore di Sanità, Via Giano della Bella 34, Rome, Italy. carlo.petrini@iss.it

No abstract available

Comment on

Questioning the methodologic superiority of 'placebo' over 'active' controlled trials.
Howick J. Howick J. Am J Bioeth. 2009 Sep;9(9):34-48. doi: 10.1080/15265160903090041. Am J Bioeth. 2009. PMID: 19998192

Research, medicine, and "placebos".
Moerman DE. Moerman DE. Am J Bioeth. 2009 Sep;9(9):64-5. doi: 10.1080/15265160903090090. Am J Bioeth. 2009. PMID: 19998201 No abstract available.
Conflating scientific with clinical considerations.
van der Graaf R, van Delden JJ. van der Graaf R, et al. Am J Bioeth. 2009 Sep;9(9):58-9. doi: 10.1080/15265160903098598. Am J Bioeth. 2009. PMID: 19998198 No abstract available.
A clinical perspective on placebo research: looking back, looking forward.
Dworkin RW. Dworkin RW. Am J Bioeth. 2009 Sep;9(9):54-5. doi: 10.1080/15265160903090108. Am J Bioeth. 2009. PMID: 19998196 No abstract available.
Those famous red pills-Deliberations and hesitations. Ethics of placebo use in therapeutic and research settings.
Touwen DP, Engberts DP. Touwen DP, et al. Eur Neuropsychopharmacol. 2012 Nov;22(11):775-81. doi: 10.1016/j.euroneuro.2012.03.005. Epub 2012 Apr 23. Eur Neuropsychopharmacol. 2012. PMID: 22534614 Review.
Are placebo-controlled trials still important for obsessive compulsive disorder?
Fineberg NA, Hawley CJ, Gale TM. Fineberg NA, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2006 May;30(3):413-22. doi: 10.1016/j.pnpbp.2005.11.012. Epub 2006 Jan 18. Prog Neuropsychopharmacol Biol Psychiatry. 2006. PMID: 16413647 Review.