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Review
. 1991;30(1):1-19.
doi: 10.1007/BF01595570.

Identification of human genes involved in repair and tolerance of DNA damage

B Kaina  1 , G Fritz, T Coquerelle
Affiliations
Review

Identification of human genes involved in repair and tolerance of DNA damage

B Kaina et al. Radiat Environ Biophys. 1991.

Abstract

An overview is presented on strategies of cloning mammalian DNA repair genes. Complementation of human and rodent repair defects and mutagen hypersensitivities by chromosome and DNA mediated gene transfer and mRNA microinjection is described, and the features of the cloned human DNA repair genes are summarized. It is shown that transfection of repair deficient cell lines with cloned bacterial and human genes may give rise to protection from the genotoxic effects of mutagens.

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References

    1. Proc Natl Acad Sci U S A. 1981 Jun;78(6):3734-7 - PubMed
    1. Somat Cell Mol Genet. 1988 Nov;14(6):605-12 - PubMed
    1. Proc Natl Acad Sci U S A. 1986 Sep;83(17):6292-6 - PubMed
    1. Carcinogenesis. 1980 Jan;1(1):21-32 - PubMed
    1. Biochem Biophys Res Commun. 1989 Apr 28;160(2):647-55 - PubMed

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