DNA: a model compound for solution studies of macromolecules
- PMID: 2000490
- DOI: 10.1126/science.2000490
DNA: a model compound for solution studies of macromolecules
Abstract
Well-defined, monodisperse, homologous series of oligonucleotides and DNA restriction fragments may now be produced and used as models of rigid and semirigid rodlike molecules in solution. Information from optical experiments on these model systems aids in the formulation and testing of theories of macromolecular dynamics in both dilute and concentrated solution.