Comment
doi: 10.1016/j.cell.2009.11.041.
A tethering complex recruits SNAREs and grabs vesicles
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- PMID: 20005800
- DOI: 10.1016/j.cell.2009.11.041
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Comment
A tethering complex recruits SNAREs and grabs vesicles
Cell.
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Free article
Abstract
Protein tethers can bridge gaps between membranes. Ren et al. (2009) now provide evidence that the yeast Dsl1 complex tethers vesicles to the endoplasmic reticulum (ER) by binding ER SNARE proteins at its base and capturing vesicles using a loop region that extends 20 nm from the ER membrane.
Comment on
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A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1.Cell. 2009 Dec 11;139(6):1119-29. doi: 10.1016/j.cell.2009.11.002. Cell. 2009. PMID: 20005805 Free PMC article.
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